341: Allogeneic Antibodies Specifically Target AML Antigen NuSAP1 after Bone Marrow Transplantation
نویسندگان
چکیده
منابع مشابه
Antibodies specifically target AML antigen NuSAP1 after allogeneic bone marrow transplantation.
Identifying the targets of immune response after allogeneic hematopoietic cell transplantation (HCT) promises to provide relevant immune therapy candidate proteins. We used protein microarrays to serologically identify nucleolar and spindle-associated protein 1 (NuSAP1) and chromatin assembly factor 1, subunit B (p60; CHAF1b) as targets of new antibody responses that developed after allogeneic ...
متن کاملGeneralized vitiligo after allogeneic bone marrow transplantation.
Sir, Vitiligo is a common, depigmenting disorder characterized by well-circumscribed cutaneous macules devoid of melanocytes on the epidermis. Bone marrow transplantation (BMT), which has significant therapeutic benefits in haematologic disorders, such as leukaemia and aplastic anaemia, provides convincing evidence for the role of the immune system in some autoimmune diseases (1). In this repor...
متن کاملAllogeneic Bone Marrow Transplantation
A 1 3-yr-old male with acute myelogenous therapy. Then, 53 yr later, he developed leukemia was treated with various chemoan extramedullary relapse with a chlotherapy regimens for 3 yr and then underroma of his maxillary sinus. This case ilwent an allogeneic bone marrow translustrates the need for prolonged followup plantation. The donor marrow was sucof transplant recipients and suggests that c...
متن کاملCytomegalovirus infection after autologous bone marrow transplantation with comparison to infection after allogeneic bone marrow transplantation.
Cytomegalovirus (CMV) infection was detected in 65 of 143 (45%) autologous bone marrow transplant (BMT) patients. CMV pneumonitis occurred in only 2% of the patients and CMV retinitis occurred in none. Infection occurred in half of the 40 initially seronegative patients and 47% of the 94 initially seropositive patients. Among initially seropositive patients, platelet recovery was slower in infe...
متن کاملGranulocytic Sarcoma by AML M4eo (inv16) after Allogeneic Stem Cell Transplantation without Bone Marrow Involvement
Granulocytic sarcoma (GS) represents a rare type of extramedullar manifestation from the acute myeloid leukaemia (AML). We report the case of a patient with recurrences of AML M4eo leukaemia in the uterus and the small intestine at 3 and 5 years, respectively, after matched related peripheral blood stem cell transplantation (PBSCT). The patient underwent the withdrawal of immunosuppression, hys...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biology of Blood and Marrow Transplantation
سال: 2008
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2007.12.351